CSN5i-3

• Target :

  Apoptosis|||Others

• Related Pathways :

  Others|||Apoptosis

• Purity :

  >99.99%

• Bioactivity :

  CSN5i-3 is a potent, selective, and orally available inhibitor of the proteolytic subunit of the CSN complex, CSN5. It inhibits CSN-catalyzed Cul1 deneddylation with an IC50 value of 5.8 nM. CSN5i-3 has a killing effect on a variety of cancer cells and can be used as an anticancer drug. [2]

• Smiles :

  CC(C)n1nc(cc1C(=O)Nc1ccc([C@H]2[C@@H](O)CCCc3cncn23)c(c1)-c1ccccc1)C(F)F

• Molecular Formula :

  C28H29F2N5O2

• Molecular Weight :

  505.56

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2375740-98-8