CHMFL-ABL/KIT-155

CAT: 0931-MF-0004974-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0004974-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2081093-21-0
Target
Bcr-Abl|||c-Kit|||PDGFR|||Discoidin Domain Receptor (DDR) |||Apoptosis
Related Pathways
Apoptosis|||Angiogenesis|||Cytoskeletal Signaling|||Tyrosine Kinase/Adaptors
Bioactivity
CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM) . It arrests cell cycle progression and induces apoptosis.
Smiles
C(C1=C(C(F)(F)F)C=C(C(NC2=CC(OC3CCN(C(=O)C=4C=CC(C)=NC4)CC3)=C(C)C=C2)=O)C=C1)N5CCN(C)CC5
Molecular Formula
C33H38F3N5O3
Molecular Weight
609.68
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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MBS5766343CHMFL-ABL/KIT-155
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A12421-100CHMFL-ABL/KIT-155 100mg
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A12421-10CHMFL-ABL/KIT-155 10mg
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