C-Kit-IN-2

• Target:

  C-Kit

• Related Pathways:

  Tyrosine Kinase/Adaptors

• Bioactivity:

  C-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM) exhibiting superior antiproliferative activities against all three GIST cell lines, GIST430, GIST882, and GIST48 (GI50s: 1, 3, and 2 nM) .

• Smiles:

  N(C=1SC(=CN1)C2=CC=C(NC(NC=3C=C(CC)ON3)=O)C=C2)C=4C=C(N=CN4)N5CCN(CC)CC5

• Molecular Formula:

  C25H29N9O2S

• Molecular Weight:

  519.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2121515-37-3