BM 957

• Target:

  Bcl-2 Family

• Related Pathways:

  Apoptosis

• Bioactivity:

  BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM) .

• Smiles:

  C(O)(=O)C=1C(=C(N(CC)C1C)C2=CC=C(Cl)C=C2)C3=CC(=CC=C3)N4CCN(CC4)C5=CC=C(NS(=O)(=O)C6=CC(S(C(F)(F)F)(=O)=O)=C(N[C@H](CCN7CCC(O)CC7)CSC8=CC=CC=C8)C=C6)C=C5

• Molecular Formula:

  C52H56ClF3N6O7S3

• Molecular Weight:

  1065.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1391107-54-2