BM 957

• Target:

  Bcl-2 Family

• Related Pathways:

  Apoptosis

• Bioactivity:

  BM 957 is an effective Bcl-2 and Bcl-xL inhibitor (Kis: 1.2 and <1 nM; IC50s: 5.4 and 6.0 nM) .

• Smiles:

  C (O) (=O) C=1C (=C (N (CC) C1C) C2=CC=C (Cl) C=C2) C3=CC (=CC=C3) N4CCN (CC4) C5=CC=C (NS (=O) (=O) C6=CC (S (C (F) (F) F) (=O) =O) =C (N[C@H] (CCN7CCC (O) CC7) CSC8=CC=CC=C8) C=C6) C=C5

• Molecular Formula:

  C52H56ClF3N6O7S3

• Molecular Weight:

  1065.68

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1391107-54-2