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AZ12601011

CAT: 0931-T10426-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T10426-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2748337-86-0
Target
ALK, TGF-beta/Smad
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, Stem Cells
Purity
0.9881
Bioactivity
AZ12601011 is an orally active, selective and potent TGFBR1 kinase inhibitor.AZ12601011 inhibits the release of inflammatory factors, interleukin (IL) -1β, IL-6 and tumor necrosis factor-α, and inhibits the growth of breast tumors.AZ12601011 directly binds to TGF-βR1 and blocks downstream Smad3 activation, which can be used to prevent renal fibrosis.
Smiles
N=1C=CC2=C(C1)C=CN2C3=NC(=NC4=C3CCC4)C5=NC=CC=C5
Molecular Formula
C19H15N5
Molecular Weight
313.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Alternative Products

CatalogName
BA9159-5.1AZ12601011
M32795-01AZ12601011 B

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