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AZ12601011

CAT: 0013-GTR19206527-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206527-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AZ12601011 is a potent, selective, and orally bioavailable TGF-β receptor 1 (TGFBR1) kinase inhibitor. It binds directly to TGFBR1, blocking Smad3 signaling, which underlies its demonstrated activity in reducing inflammatory cytokine release and inhibiting tumor growth in breast cancer models, as well as its potential in preventing renal fibrosis.
CAS Number
2748337-86-0
Product Name Alternative
ALK4, AZ 12601011, AZ12601011, AZ-12601011, TGF-b/Smad, TGFb, TGF-beta, TGFbeta, TGFbeta/Smad, TGFBR1, Smad, TGF-β/Smad, TGFβR1, TGFβ
Field of Research
Cardiovascular Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.81% (May vary between batches)
Solubility
DMSO:4 mg/mL (12.76 mM)
Smiles
N=1C=CC2=C (C1) C=CN2C3=NC (=NC4=C3CCC4) C5=NC=CC=C5
Molecular Formula
C19H15N5
Molecular Weight
313.36
Storage Conditions
-20°C
Notes
For research use only.

Alternative Products

CatalogName
BA9159-5.1AZ12601011
M32795-01AZ12601011 B

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