AC710 Mesylate

• Target:

  PDGFR

• Related Pathways:

  Angiogenesis|||Tyrosine Kinase/Adaptors

• Bioactivity:

  AC710 Mesylate is a potent PDGFR inhibitor with dissociation constants (Kds) of 0.6 nM for FLT3, 1.57 nM for CSF1R, 1 nM for KIT, 1.3 nM for PDGFR?, and 1.0 nM for PDGFR?.

• Smiles:

  O=C(NC1=NOC(=C1)C(C)(C)C)NC2=CC=C(C=C2)NC(=O)C3=NC=C(OC4CC(N(CC)C(C)(C)C4)(C)C)C=C3.O=S(=O)(O)C

• Molecular Formula:

  C32H46N6O7S

• Molecular Weight:

  658.81

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1351522-05-8