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Nilutamide

CAT: 0931-T0272-03Size: 200 mgDry Ice: NoHazardous: No
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CAT#:0931-T0272-03Size:200 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
63612-50-0
Target
Androgen Receptor, Parasite
Related Pathways
Microbiology/Virology, Endocrinology/Hormones
Purity
0.9978
Bioactivity
Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progestogen, or glucocorticoid receptors. Therefore, Nilutamide can block the action of androgens of testicular and adrenal origin that stimulate the growth of malignant and normal prostatic tissue. Prostate Y is mainly androgen-dependent and can be treat with chemical castration or surgical. So far, antiandrogen monotherapy has not consistently been certified to be equivalent to castration.
Smiles
O=C1N(C(=O)NC1(C)C)C2=CC(C(F)(F)F)=C(N(=O)=O)C=C2
Molecular Formula
C12H10F3N3O4
Molecular Weight
317.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

Nilutamide

Nilutamide is a C-nitro compound, an imidazolidinone and a member of (trifluoromethyl)benzenes. It has a role as an androgen antagonist and an antineoplastic agent.

CAS Number63612-50-0
PubChem CID4493
IUPAC Name5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
Molecular FormulaC12H10F3N3O4
Molecular Weight317.22
XLogP2
Topological Polar Surface Area95.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count1
Heavy Atom Count22
Formal Charge0
Complexity515
SMILES
CC1(C(=O)N(C(=O)N1)C2=CC(=C(C=C2)[N+](=O)[O-])C(F)(F)F)C
InChI
InChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChIKey
XWXYUMMDTVBTOU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Nilutamide
CAS: 63612-50-0
CID: 4493
Formula: C12H10F3N3O4
MW: 317.22
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight317.22
XLogP32
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count1
Exact Mass317.06234029
Monoisotopic Mass317.06234029
Topological Polar Surface Area95.2 Ų
Heavy Atom Count22
Formal Charge0
Complexity515
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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A21165-200Nilutamide 200mg
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