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Chromium picolinate (Standard)

CAT: 0804-HY-125588R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-125588R-01Size:10 mg
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Description
Chromium picolinate (Standard) is the analytical standard of Chromium picolinate. This product is intended for research and analytical applications. Chromium picolinate (Chromium (III) picolinate) is a compound that has oral activity. Chromium picolinate induces apoptosis. Chromium picolinate is the activator of p38 MAPK. Chromium picolinate has antioxidant activity. Chromium picolinate can be used in research on type 2 diabetes[1][2][3][4].
CAS Number
14639-25-9
Product Name Alternative
Chromium (III) picolinate (Standard) ; Cr (Pic) 3 (Standard)
UNSPSC
12352005
Target
Apoptosis; p38 MAPK; Reference Standards
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/chromium-picolinate-standard.html
Smiles
O=C1[O-][Cr+3]([N]2=C(C=CC=C2)C3=O)([O-]3)([N]4=C(C=CC=C4)C5=O)([O-]5)[N]6=C1C=CC=C6
Molecular Formula
C18H12CrN3O6
Molecular Weight
418.30
References & Citations
[1]Jana M, et al. Chromium picolinate induced apoptosis of lymphocytes and the signaling mechanisms thereof. Toxicol Appl Pharmacol. 2009 Jun 15;237 (3) :331-44.|[2]Wang YQ, et al. Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK. J Nutr Biochem. 2009 Dec;20 (12) :982-91.|[3]Kim DS, et al. Chromium picolinate supplementation improves insulin sensitivity in Goto-Kakizaki diabetic rats. J Trace Elem Med Biol. 2004;17 (4) :243-7.|[4]Sundaram B, et al. Chromium picolinate attenuates hyperglycemia-induced oxidative stress in streptozotocin-induced diabetic rats. J Trace Elem Med Biol. 2013 Apr;27 (2) :117-21.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Chemical Information

Chromium(III) picolinate

Chromium picolinate has a chemical formula CrPic3 and reddish-pink color. It is a coordination complex consisting of chromium(III) and picolinic acid. Chromium picolinate is used as a nutritional supplement for optimal insulin function in patients with Type 2 diabetes or promotion of weight loss. Chromium ions are shown to regulate insulin by promoting glucose utilization and increasing the sensitivity of the insulin receptor.

CAS Number14639-25-9
PubChem CID151932
IUPAC Namechromium(3+);tris(pyridine-2-carboxylate)
Molecular FormulaC18H12CrN3O6
Molecular Weight418.3
Topological Polar Surface Area159
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count9
Rotatable Bond Count0
Heavy Atom Count28
Formal Charge0
Complexity108
SMILES
C1=CC=NC(=C1)C(=O)[O-].C1=CC=NC(=C1)C(=O)[O-].C1=CC=NC(=C1)C(=O)[O-].[Cr+3]
InChI
InChI=1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
InChIKey
CBDQOLKNTOMMTL-UHFFFAOYSA-K
Chemical Structure
2D Structure
2D structure of Chromium(III) picolinate
CAS: 14639-25-9
CID: 151932
Formula: C18H12CrN3O6
MW: 418.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight418.3
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count9
Rotatable Bond Count0
Exact Mass418.013115
Monoisotopic Mass418.013115
Topological Polar Surface Area159 Ų
Heavy Atom Count28
Formal Charge0
Complexity108
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count4
Compound Is CanonicalizedYes

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