Chromium picolinate

Chromium picolinate

• Alternative Name: Chromium (III) picolinate; Cr(Pic)3
• CAS Number: 14639-25-9
• UNSPSC Description: Chromium picolinate (Chromium (III) picolinate) is a compound that has oral activity. Chromium picolinate induces apoptosis. Chromium picolinate is the activator of p38 MAPK. Chromium picolinate has antioxidant activity. Chromium picolinate can be used in research on type 2 diabetes[1][2][3][4].
• Target Antigen: Apoptosis; p38 MAPK
• Type: Reference compound
• Related Pathways: Apoptosis;MAPK/ERK Pathway
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/chromium-picolinate.html
• Purity: 99.76
• Solubility: DMSO : 7.81 mg/mL (ultrasonic)
• Smiles: O=C1[O-][Cr+3]([N]2=C(C=CC=C2)C3=O)([O-]3)([N]4=C(C=CC=C4)C5=O)([O-]5)[N]6=C1C=CC=C6
• Molecular Weight: 418.30
• References & Citations: [1]Jana M, et al. Chromium picolinate induced apoptosis of lymphocytes and the signaling mechanisms thereof. Toxicol Appl Pharmacol. 2009 Jun 15;237(3):331-44.|[2]Wang YQ, et al. Effects of chromium picolinate on glucose uptake in insulin-resistant 3T3-L1 adipocytes involve activation of p38 MAPK. J Nutr Biochem. 2009 Dec;20(12):982-91.|[3]Kim DS, et al. Chromium picolinate supplementation improves insulin sensitivity in Goto-Kakizaki diabetic rats. J Trace Elem Med Biol. 2004;17(4):243-7.|[4]Sundaram B, et al. Chromium picolinate attenuates hyperglycemia-induced oxidative stress in streptozotocin-induced diabetic rats. J Trace Elem Med Biol. 2013 Apr;27(2):117-21.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Launched