Products for Research Use Only

MMP-14, Active, Human Recombinant

CAT: 0026-8009-50Size: 50 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-8009-50Size:50 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
The Matrix metalloproteinase-14 (MMP-14) belongs to a family of zinc-dependent endopeptidases. The ability of MMP-14 to degrade type I collagen, and activate pro-MMP-2 and pro-MMP-9 makes it a key enzyme in many physiological and pathological processes such as angiogenesis and tumor invasion. MMP-14 is structurally a multi-domain metalloenzyme, composed of a prodomain, a metal-binding catalytic domain, a hinge region, a hemopexin-like domain, a transmembrane domain, and a cytoplamasic tail. The catalytic, and hinge domains of MT1-MMP were expressed in Escherichia coli and the active form was generated by successive autoproteolysis of the N- and C-terminal sites during refolding.
CAS Number
9000-83-3
Shipping Conditions
Gel Pack
Storage Conditions
-20°C
Shelf Life
12 months