Irisin, Active, human recombinant

Irisin, Active, human recombinant

• Description: Irisin is a recently discovered exercise-induced myokine, which is secreted by skeletal muscles and produced by cleavage of the FNDC5. Studies show that Irisin stimulates mitochondria uncoupling protein-1 (UCP-1; a regulator of thermogenic capability of brown fat) expression, so Irisin can upregulate white to brown fat conversion and improve systemic metabolism by increasing energy expenditure. Hence, Irisin is a potential new drug target in the study of metabolic disorders, such as obesity and type 2 diabetes mellitus (T2DM). Moreover, FNDC5-like receptors are conserved in vertebrates and critical for neuronal development.
• CAS Number: 9000-83-3
• Shipping Conditions: Gel Pack
• Storage Conditions: -20°C
• Shelf Life: 12 months