Granzyme B, Mouse recombinant (Insect)

• Description:

  Granzyme B (GZMB) is a serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and enters the target cell, assisted by perforin. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell.

• Shipping Conditions:

  dry ice

• Storage Conditions:

  -70°C

• Shelf Life:

  12 months

• CAS Number:

  9000-83-3