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SRT-3025 hydrochloride

CAT: 0026-B2376-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2376-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SRT-3025 is a potent and selective Sirt1 activator. It inhibits RANKL-induced osteoclast differentiation, fusion and resorptive capacity without affecting osteoclast survival. SRT-3025 inhibits RANKL-induced osteoclastogenesis in bone marrow-derived macrophages (BMMs) by activating AMPK and deacetylating RelA/p65 lysine 310, critical for activation of the NF-κB signaling pathway.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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