PF-562271 besylate

CAT: 0026-B1253-25Size: 25 mgDry Ice: NoHazardous: No
CAT#:0026-B1253-25Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
F-562271 is an ATP-competitive, reversible inhibitor of FAK (IC₅₀ = 1.5 nM). It displays 10-fold reduced potency for PYK2 (IC₅₀ = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC₅₀ value of 93 ng/ml in glioblastoma-bearing mice and has been shown to regress tumors in multiple xenograft models.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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