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Entacapone

CAT: 0026-B1190-10Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0026-B1190-10Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Entacapone is a potent catechol O-methyl transferase (COMT) inhibitor with IC₅₀ values of 14.3, 20.1 and 73.3 nM for rat liver soluble COMT, total COMT and membrane-bound COMT, respectively. Entacapone inhibits aggregation of α-synuclein in an in vitro assay and shown to block α-synuclein induced cell death in PC-12 cells. In vivo studies have shown that it increases the bioavailability of levodopa when given as an adjunct therapy for Parkinson’s disease.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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