JNJ-10198409

CAT: 0026-B1078-5Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0026-B1078-5Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

JNJ-10198409 is a potent, cell-permeable, ATP-competitive inhibitor of Platelet-Derived Growth Factor receptor tyrosine kinase (PDGF-RTK) with both antiangiogenic and a direct tumor cell antiproliferative activity. It is selective for PDGF-β kinase with IC₅₀ values of 4.2 nM for PDGF-β and 45 nM for PDGF-α kinase. Displays less activity towards Lck, c-Src, and Fyn while exhibiting little to no inhibition toward VEGFR, HER-2, Cdk's-1,-2,-4 &-7, bFGFR-1 and EGFR.

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

36 months

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A22554-200	JNJ-10198409 200mg
A22554-100	JNJ-10198409 100mg
A22554-25	JNJ-10198409 25mg
A22554-1	JNJ-10198409 1mg
A22554-5	JNJ-10198409 5mg
A22554-50	JNJ-10198409 50mg

JNJ-10198409

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