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PX-478 hydrochloride

CAT: 0026-B1033-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B1033-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PX-478 hydrochloride is an inhibitor of HIF-1α (IC₅₀ of 20-30 μM) with potential antineoplastic activity. PX-478 inhibits HIF-1alpha protein levels and transactivation in a variety of cancer cell lines. The inhibitory effect of PX-478 on HIF-1alpha levels is primarily due to its inhibition of translation because HIF-1alpha translation continues in hypoxia when translation of most proteins is decreased.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
36 months

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