Dextromethorphan (hydrobromide hydrate)

• Description:

  Dextromethorphan (DXM) is a morphinan with structural similarity to levorphanol, codeine, and morphine. DXM binds to and inhibits NMDA (IC50 = 0.55 μM) and nicotinic receptors (IC50s = 0.7-3.9 μM) and blocks receptor-gated and voltage-gated calcium channels (IC50 = 60 μM) and voltage-gated sodium channels (IC50 = 78 μM). It is a Cytochrome P450 2D6 substrate and it is converted into the active metabolite dextrorphan in the liver.

• Shipping Conditions:

  gel pack

• Storage Conditions:

  -20°C

• Shelf Life:

  24 months