Halofuginone hydrobromide

CAT:

26-B2610-10

Size:

10 mg

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Description: Halofuginone is an an ATP-dependent inhibitor prolyl-tRNA synthetase (Ki of 18.3 nM). Halofuginone attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Blocks expression of MMP2 and inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice. Also inhibits the development of Th17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.
Shipping Conditions: Gel Pack
Storage Conditions: -20ºC
Shelf Life: 36 months

Cat	Name
B2610-50	Halofuginone hydrobromide
B2610-10	Halofuginone hydrobromide
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