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Halofuginone hydrobromide

CAT: 0026-B2610-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-B2610-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Halofuginone is an an ATP-dependent inhibitor prolyl-tRNA synthetase (Ki of 18.3 nM). Halofuginone attenuates osteoarthritis (OA) by inhibition of TGF-β activity. Blocks expression of MMP2 and inhibits ECM invasion in vitro and lung metastasis by bladder cancer cells in mice. Also inhibits the development of Th17-driven autoimmunity in a mouse model of multiple sclerosis by activating the amino acid response (AAR) pathway.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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