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Sulfo-LC-SPDP

CAT: 0026-2325-50Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0026-2325-50Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KEY FEATURES: • Sulfo-LC-SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily followed • Amine-reactive; the "long chain" Sulfo-LC-SPDP crosslinking reagent has a 15.7 Å spacer arm • More water-soluble than the corresponding LC-SPDP • Membrane-impermeable which enables crosslinking on cell surface • The cleavable spacer arm enables separation of cross-linked products APPLICATIONS: • Reversible crosslinking of proteins • N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chains • Sulfo-LC-SPDP crosslinking molecule pyridinyldisulfide reacts with sulhydryls to yield a reversible disulfide bond.
Shipping Conditions
Gel Pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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