SPDP Crosslinker

CAT: 0026-2328-50Size: 50 mgDry Ice: NoHazardous: No
CAT#:0026-2328-50Size:50 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
KEY FEATURES: • SPDP contains a dithiopyridyl group which is reactive towards cysteines (-SH groups) and an NHS group, which is useful when targeting primary amines (-NH2 groups) • SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily followed • Contains a disulfide linkage in its spacer arm with a length of 6.8 Å • The spacer is cleavable with reducing agent, such as DTT, TCEP, etc. APPLICATIONS: • Reversible crosslinking of proteins • N-hydroxysulfosuccinimide (Sulfo-NHS) ester that reacts with primary amines, as found in lysine side chains • Useful for adding sulfhydryl groups to proteins by attachment to lysine residues • Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates
Shipping Conditions
Gel Pack
Storage Conditions
-20 ̊C
Shelf Life
36 months

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