UNC 1215

CAT: 0026-2252-5Size: 5 mgDry Ice: NoHazardous: No
CAT#:0026-2252-5Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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