Products for Research Use Only
RegisterLogin

Smo Antagonist, SA10

CAT: 0026-2159-2Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-2159-2Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SA10 inhibits SAG (Smoothened agonist) activation of Hh signaling in Shh-LIGHT 2 cells (IC₅₀ = 5 µM). However, unlike SA1 and SA9, Smo antagonist SA10 does not directly bind to Smo. Inhibits the localization o Smo to cilia. Also treatment of Ptch1-/- MEFs with SA10 suppresses the β-galactosidase activity (IC₅₀ = 11.0 µM) and inhibits the expression of Gli1 and Ptch1 in ASZ1 cells.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24months

Related Products

CatalogName
2154-5Smo Antagonist, SA1
2154-2Smo Antagonist, SA1
2155-2Smo Antagonist, SA9
2155-5Smo Antagonist, SA9
1939-1Smo Agonist, SAG
1939-5Smo Agonist, SAG
A1058-100SMO Antibody (Center)
2801-1Smo agonist, SAG dihydrochloride
2801-5Smo agonist, SAG dihydrochloride
1979-10PPARγ Antagonist, G3335

Alternative Products

CatalogName
170074-01Smo Antagonist, SA10 (4- ((Benzo[c][1,2,5]thiadiazole-4-sulfonamido) methyl-N- (3-phenylpropyl) cyclohexanecarboxamide) discontinued
TBI2441-250MGPranlukast, Leukotriene CysLT1 antagonist; GPR17 antagonist
TBI2597-50MGMontelukast, Leukotriene CysLT1 antagonist; GPR17 antagonist
cyt-538-01chGH Antagonist
cyt-215-01oGH Antagonist
4031352.0500VIP Antagonist
H-8650.0005PDGF Antagonist
JLB39188-01Vasopressin antagonist
254641Antagonist G
T36127-01TNF-α Antagonist

Popular Products