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Puromycin Dihydrochloride

CAT: 0026-1860-1000Size: 1 gDry Ice: NoHazardous: No
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CAT#:0026-1860-1000Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 µg/ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 µg/ml.
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months