DAPT

CAT: 0026-1855-5Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0026-1855-5Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Cell permeable. A potent inhibitor of γ-secretase (IC₅₀ = 115 nM for total β-amyloid, IC₅₀ = 200 nM for β-amyloid 1-42). It reduces Aβ levels in vivo in plasma and cerebrospinal fluid in young and aged Tg2576 mice. Antagonizes Notch signaling through inhibition of Notch processing. DAPT treatment can influence hematopoietic cell fate decisions and enhances neuronal differentiation in embryonic stem cell-derived embryoid bodies independent of sonic hedgehog (shh) signaling.

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

24 months

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Alternative Products

Catalog	Name
S2215-25mg	DAPT

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