Lactacystin (Synthetic)

CAT:

26-1709-200

Size:

200 µg

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Description: Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2A neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-kB activation (IC₅₀ = 10 µM).
Shipping Conditions: gel pack
Storage Conditions: -20°C
Shelf Life: 24 months

Cat	Name
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