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Lactacystin (Natural)

CAT: 0026-2434-200Size: 200 µgDry Ice: NoHazardous: No
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CAT#:0026-2434-200Size:200 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. A potent and selective inhibitor of the 20 S proteasome. Binds irreversibly to the active site N-terminal threonine residue of the catalytic β-subunit of the 20S proteasome, thereby inhibiting its chymotrypsin and trypsin-like activities. Induces neurite outgrowth in Neuro 2A neuroblastoma cells and has been reported to induce apoptosis in human monoblast U937 cells. Also inhibits NF-kB activation (IC₅₀ = 10 µM).
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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