Lactacystin

• Target :

  Protease|||Apoptosis|||cAMP

• Related Pathways :

  GPCR/G Protein|||Proteases/Proteasome|||Apoptosis

• Bioactivity :

  Lactacystin is an orally active, irreversible, and cell-permeable proteasome inhibitor (IC50 = 4.8 ?M) that also inhibits the lysosomal enzyme cathepsin A. It induces apoptosis and cell cycle arrest, possesses anticancer, antiviral, and antioxidant activities, can penetrate the blood-brain barrier, and is commonly used in the construction of Parkinson’s disease and dementia models.

• Smiles :

  C(SC[C@H](NC(C)=O)C(O)=O)(=O)[C@@]1([C@H](C(C)C)O)[C@@H](O)[C@@H](C)C(=O)N1

• Molecular Formula :

  C15H24N2O7S

• Molecular Weight :

  376.43

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  133343-34-7