Products for Research Use Only
RegisterLogin

HDAC8 Inhibitor Screening Kit (Fluorometric)

CAT: 0026-K368-100Size: 100 AssaysDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0026-K368-100Size:100 Assays
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC-8 Inhibitor screening Kit, HDAC-8 deacetylates the substrate (R-H-K(Ac)-K(Ac)-AFC) followed by an enzymatic cleavage to release the quenched fluorescent group (AFC), which can be detected at Em/Ex = 380/500 nm. In the presence of an HDAC-8 inhibitor, the deacetylation will be impeded which prevents the cleavage of the substrate to release AFC. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput screening of HDAC-8 inhibitors. Trichostatin A is included as a control inhibitor to compare the efficacy of the test inhibitors.
Features & Benefits
• Simple procedure; takes ~ 60 min • Fast and convenient • Kit contains the necessary reagents for testing putative HDAC-8 inhibitors
Shipping Conditions
gel pack
Storage Conditions
-20°C
Shelf Life
12 months

Related Products

CatalogName
K363-100HDAC3 Inhibitor Screening Kit (Fluorometric)
K465-100HDAC6 Inhibitor Screening Kit (Fluorometric)
K171-100HDAC-5 Inhibitor Screening Kit (Fluorometric)
K340-100HDAC Inhibitor Drug Screening Kit (Fluorometric)
K382-100Plasmin Inhibitor Screening Kit (Fluorometric)
K833-100Collagenase Inhibitor Screening Kit (Fluorometric)
K727-100Urokinase Inhibitor Screening Kit (Fluorometric)
K345-100pCAF Inhibitor Screening Kit (Fluorometric)
K374-100Thrombin Inhibitor Screening Kit (Fluorometric)
K780-100DPP4 Inhibitor Screening Kit (Fluorometric)

Alternative Products

CatalogName
55R-1387HDAC8 Inhibitor Drug Screening Kit
K2038-100HDAC Inhibitor Drug Screening Kit (Fluorometric)
K2088-100CETP Inhibitor Drug Screening Kit (Fluorometric)
K2156-100Cathepsin D Inhibitor Screening Kit (Fluorometric)
167870HDAC8 Inhibitor, BioAssayTM Screening Kit discontinued
TBS2099-100Adenosylhomocysteine (AHCY) Inhibitor Screening Assay Kit (Fluorometric)
TBS2097-100NNMT Inhibitor Screening Assay Kit (Colorimetric / Fluorometric)
301293Thrombin Inhibitor, Fluorometric Screening BioAssayTM Kit discontinued
301286SIRT6 Inhibitor, Fluorometric, Screening BioAssayTM Kit discontinued
K2163-100Caspase-7 Inhibitor Drug Screening Kit (Fluorometric)

Popular Products