Products for Research Use Only
RegisterLogin

5-Hydroxylansoprazole

CAT: 0804-HY-118283-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-118283-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatment of various peptic diseases[1][2].
CAS Number
131926-98-2
Product Name Alternative
AG1908
UNSPSC
12352005
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/5-hydroxylansoprazole.html
Purity
99.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC1=CC=C2N=C(NC2=C1)S(CC3=NC=CC(OCC(F)(F)F)=C3C)=O
Molecular Formula
C16H14F3N3O3S
Molecular Weight
385.36
References & Citations
[1]Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48 (8) :947-52. doi: 10.3109/13880200903300220.|[2]Katarína Kostolanská, et al. Determination of lansoprazole, 5-hydroxylansoprazole, and lansoprazole sulfone in human plasma for CYP2C19 and CYP3A4 phenotyping. Chemical Papers. volume 73, pages2955–2963 (2019) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-160457-01FABP4/5-IN-5
HY-1494765-LOX-IN-5
HY-N85815,5'-Dimethoxysecoisolariciresinol
HY-N26485,5'-Dimethoxylariciresinol
HY-1543445′-Deoxy-5′-iodo-5-methyluridine
HY-W037549-015,5,5-Trifluoro-DL-leucine
HY-1543465’-Azido-5’-deoxy-5-methyluridine
HY-1543454′,5′-Didehydro-5′-deoxy-5-methyluridine
HY-D1539-01Cyanine 5.5 azide
HY-D1639A5,5'-Dibromo-BAPTA

Alternative Products

CatalogName
BA6942-105-Hydroxylansoprazole
MBS57733505-Hydroxylansoprazole sulfone
sc-2627255,5,5-Trifluorovaleronitrile
234404-015,5,5-Trifluoronorvaline
PDA866615,5,5-Trifluoropentanonitrile
JH2382995,5,5-trifluoroleucine
AKA25347-015,5,5-Trifluoropentanal
TRC-F632600-2.5GN-Fmoc-5,5,5,5',5',5'-Hexafluoro-L-leucine
OR1058406-015,5',5'',5'''-Methanetetrayltetrakis (2-hydroxybenzaldehyde)
459053N-Fmoc-5,5,5,5',5',5'-Hexafluoro-L-leucine discontinued

Popular Products