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Recombinant c-Myc Antibody

CAT: 0013-GTR18572224-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18572224-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
It recognizes a transcription factor of 64-67kDa, identified as c-myc. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.
UniProt
P01106
Reactivity
Human
Immunogen
A recombinant fragment of human MYC protein was used as the immunogen for the recombinant c-Myc antibody.
Clonality
Recombinant
Clone
MYC/7150R
Conjugation
Unconjugated
Field of Research
Cancer Biology
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant c-Myc antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Rabbit
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Rabbit IgG, kappa

UniProtKB · P01106

Myc proto-oncogene protein

MYC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P01106
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MYC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A0A024R9L7, A0A087WUS5, A8WFE7, H0YBT0, P01107, Q14026
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

PTM

AcetylationGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-binding

Coding sequence diversity

Alternative initiationAlternative splicingChromosomal rearrangement

Cellular component

ChromosomeCytoplasmNucleus

Disease

Proto-oncogene

Biological process

TranscriptionTranscription regulation

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