Recombinant c Myc Monoclonal Antibody

• Background:

  This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.

• Description:

  This is a Recombinant c Myc Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  AU016757, Avian myelocytomatosis viral oncogene homolog, bHLHe39, c Myc, Class E basic helix-loop-helix protein 39, MRTL, Myc, Myc protein, Myc proto oncogene protein, Myc proto-oncogene protein, myc-related translation/localization regulatory factor, MYC, Myc2, MYCC

• Gene ID:

  4609

• Swiss Prot:

  P01106

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human c-Myc

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:1000-1:2000

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  32kDa

• Observed Molecular Weight:

  32kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG