Products for Research Use Only

CCL8 Antibody / MCP2

CAT: 0013-GTR18571232-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18571232-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
This anti-microbial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.
UniProt
P80075
Reactivity
Human
Immunogen
A portin of amino acids 1-99 from the human protein was used as the immunogen for the CCL8 antibody.
Clonality
Monoclonal
Clone
CCL8/3683
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Purification
Protein A/G affinity
Dilution
Immunohistochemistry (FFPE) : 1-2ug/ml
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the CCL8 antibody should be determined by the researcher.
Tested Applications
IHC-P
Host or Source
Mouse
Preservative
0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
Isotype
Mouse IgG2c, kappa

UniProtKB · P80075

C-C motif chemokine 8

CCL8_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P80075
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCL8
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0AV77, P78388
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Biological process

ChemotaxisInflammatory response

Molecular function

CytokineHeparin-binding

PTM

Disulfide bondPyrrolidone carboxylic acid

Cellular component

Secreted

Domain

Signal