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Recombinant GLUT1 Antibody

CAT: 0013-GTR18574757Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR18574757Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recognizes a protein of 45-55kDa, which is identified as GLUT1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut1 to Glut12. Glut1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut1 is expressed at variable levels in many human tissues. Overexpression has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative) .
UniProt
P11166
Reactivity
Human
Immunogen
A portion of amino acids 203-305 from the human protein was used as the immunogen for this recombinant GLUT1 antibody.
Clonality
Recombinant
Clone
GLUT1/3132R
Conjugation
Unconjugated
Purification
Protein G affinity chromatography
Dilution
ELISA: 1-2ug/ml for coating (order BSA/sodium azide-free format), Flow cytometry: 1-2ug/10^6 cells, Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Optimal dilution of the recombinant GLUT1 antibody should be determined by the researcher.
Tested Applications
ELISA, FACS, IHC-P
Host or Source
Rabbit
Preservative
1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Isotype
Rabbit IgG, kappa

UniProtKB · P11166

Solute carrier family 2, facilitated glucose transporter member 1

GTR1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P11166
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SLC2A1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K9S6, B2R620, D3DPX0, O75535, Q0P512, Q147X2
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationGlycoproteinPhosphoprotein

Disease

CataractDisease variantDystoniaEpilepsyHereditary hemolytic anemiaIntellectual disability

Cellular component

Cell membraneMembrane

Biological process

Sugar transportTransport

Domain

TransmembraneTransmembrane helix

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