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Pandinotoxin Kα

CAT: 0804-HY-P2949Size: 1 EachDry Ice: NoHazardous: No
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Description
Pandinotoxin Kα, isolated from the venom of Pandinus imperator, is the inhibitor of A-type potassium channel[1].
CAS Number
185529-64-0
UNSPSC
12352209
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pandinotoxin-kα.html
Solubility
10 mM in DMSO
Smiles
O=C(NC(C(C)CC)C(NC(CO)C(N[C@H](CSSCC(C(NC(CCSC)C(NC(CC(N)=O)C(NC(CCCNC(N)=N)C(NC1CCCCN)=O)=O)=O)=O)NC2=O)C(NC(C(O)C)C(N[C@@H](CC(N)=O)C(N3C(CCC3)C(N[C@@H](CCCCN)C(NC(CCC(N)=O)C(NC(CSSCC(C(NC4CCCCN)=O)NC1=O)C(NC(CC5=CC=C(C=C5)O)C(N6C(CCC6)C(NC(CC7=CNC=N7)C(N[C@H](CSSCC(C(NC(CC8=CC=CC=C8)C(NCC(NC(CCCNC(N)=N)C(O)=O)=O)=O)=O)NC4=O)C(NC(CCCCN)C(N[C@H](CCCCN)C(NC(CCC(O)=O)C(N[C@H]([C@H](O)C)C(NCC(N[C@@H](CC9=CC=C(C=C9)O)C(N%10[C@@H](CCC%10)C(NC(CC(N)=O)C(NC(C)C(NC2CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Molecular Formula
C169H267N53O48S7
Molecular Weight
4033.71
References & Citations
[1]T C Tenenholz, et al. Solution Structure for Pandinus Toxin K-α (PiTX-Kα), a Selective Blocker of A-Type Potassium Channels. Biochemistry. 1997 Mar 11;36 (10) :2763-71.|[2]Targeting Kai-Zheng Duan, et al. A-type K (+) channels in primary sensory neurons for bone cancer pain in a rat model. Pain.2012 Mar;153 (3) :562-574.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Voltage-gated potassium channel

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