Products for Research Use Only
RegisterLogin

6α-Hydroxy paclitaxel

CAT: 0804-HY-125348-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-125348-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
6α-Hydroxy paclitaxel is a primary metabolite of Paclitaxel. 6α-Hydroxy paclitaxel retains a time-dependent effect on organic anion–transporting polypeptides 1B1/SLCO1B1 (OATP1B1) with similar inhibition potency to Paclitaxel, whereas it no longer showed time-dependent inhibition of OATP1B3. 6α-Hydroxy paclitaxel can be used for the research of cancer[1].
CAS Number
153212-75-0
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/6α-hydroxy-paclitaxel.html
Purity
99.93
Solubility
DMSO : 5 mg/mL (ultrasonic; warming)
Smiles
CC(O[C@]12[C@@]([C@]3([C@@H](O)[C@H](O)[C@@]1([H])OC2)C)([H])[C@@H]([C@]4(C(C)(C([C@@H](OC(C)=O)C3=O)=C(C)[C@@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(C6=CC=CC=C6)=O)=O)C4)C)O)OC(C7=CC=CC=C7)=O)=O
Molecular Formula
C47H51NO15
Molecular Weight
869.91
Precautions
H302, H315, H319, H335
References & Citations
[1]Mori D, et al. Alteration in the Plasma Concentrations of Endogenous Organic Anion-Transporting Polypeptide 1B Biomarkers in Patients with Non-Small Cell Lung Cancer Treated with Paclitaxel. Drug Metab Dispos. 2020 May;48 (5) :387-394.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-144149S-013'-p-Hydroxy paclitaxel-d5
HY-W7404803'-p-Hydroxy paclitaxel-d5-1
HY-B0015-01Paclitaxel
HY-144561S6α,3'-p-Dihydroxy paclitaxel-d5
HY-175981Paclitaxel-bromothiophene
HY-W768912-01Paclitaxel-13C6
HY-137776Paclitaxel C
HY-177146Paclitaxel-MVCP
HY-P99974-01Nab-Paclitaxel
HY-177999Paclitaxel-DBCO

Alternative Products

CatalogName
T36896-016α-hydroxy Paclitaxel
sc-2174066α-Hydroxy Paclitaxel-d5
AR-P01001-016-alpha-Hydroxy Paclitaxel
TRC-H948890-0.5MG6-Alpha-Hydroxy Paclitaxel (~90%)
RM-P812553-016-Alpha-Hydroxy Paclitaxel-D5
2791716a-Hydroxy Paclitaxel
MBS57979216alpha-hydroxy Paclitaxel
AR-P30106-0119-Hydroxy Paclitaxel
0052762’-O- (tert-Butyldimethylsilyl) -6α-hydroxy Paclitaxel
sc-2141893'-p-Hydroxy Paclitaxel

Popular Products