Coenzyme Q10

• UNSPSC Description:

  Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

• Target Antigen:

  Endogenous Metabolite; Ferroptosis; Reactive Oxygen Species

• Type:

  Natural Products

• Related Pathways:

  Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/Coenzyme_Q10.html

• Purity:

  99.69

• Solubility:

  DMF : 20 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C)|Ethanol : 2.5 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : < 0.1 mg/mL

• Smiles:

  O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)C(C(OC)=C1OC)=O

• Molecular Weight:

  863.34

• References & Citations:

  [1]Yang YK, et al. Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clin Chim Acta. 2015 Oct 23;450:83-9.|[2]Bhagavan HN, et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006 May;40(5):445-53.|[3]Matthews RT, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95(15):8892-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  Launched

• CAS Number:

  303-98-0