Coenzyme Q10

• Description :

  Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.

• Product Name Alternative :

  CoQ10; Ubiquinone-10; Ubidecarenone

• UNSPSC :

  12352211

• Hazard Statement :

  H315, H319, H320

• Target :

  Endogenous Metabolite; Ferroptosis; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/Coenzyme_Q10.html

• Purity :

  99.69

• Solubility :

  DMF : 20 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C1C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=C(C)C(C(OC)=C1OC)=O

• Molecular Formula :

  C59H90O4

• Molecular Weight :

  863.34

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Yang YK, et al. Coenzyme Q10 treatment of cardiovascular disorders of ageing including heart failure, hypertension and endothelial dysfunction. Clin Chim Acta. 2015 Oct 23;450:83-9.|[2]Bhagavan HN, et al. Coenzyme Q10: absorption, tissue uptake, metabolism and pharmacokinetics. Free Radic Res. 2006 May;40 (5) :445-53.|[3]Matthews RT, et al. Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects. Proc Natl Acad Sci U S A. 1998 Jul 21;95 (15) :8892-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C (Powder, sealed storage, away from moisture and light)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [303-98-0]