Coenzyme A

CAT: 0804-HY-128851-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-128851-01Size:5 mg
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Description
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].
CAS Number
[85-61-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Fatty Acid Synthase (FASN)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/coenzyme-a.html
Purity
97.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC([C@H](C(NCCC(NCCS)=O)=O)O)(C)COP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1OP(O)(O)=O)(O)=O)(O)=O
Molecular Formula
C21H36N7O16P3S
Molecular Weight
767.53
Precautions
H302, H315, H319, H335
References & Citations
[1]Roberta Leonardi, et al. Coenzyme A: back in action. Prog Lipid Res. 2005 Mar-May;44 (2-3) :125-5.|[2]Tsuchiya Y, et al. Protein CoAlation and antioxidant function of coenzyme A in prokaryotic cells. Biochem J. 2018 Jun 6;475 (11) :1909-1937.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
Phase 4

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