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Coenzyme Q0

CAT: 0931-T127402-01Size: 1 gDry Ice: NoHazardous: No
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CAT#:0931-T127402-01Size:1 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
605-94-7
Target
Others, ROS, Interleukin, mTOR, MMP, COX, Autophagy, EGFR, Reactive Oxygen Species, Caspase, NF-κB, PARP, Akt, Bcl-2 Family, Apoptosis, TNF, NO Synthase
Related Pathways
JAK/STAT signaling, PI3K/Akt/mTOR signaling, NF-κB, Tyrosine Kinase/Adaptors, Angiogenesis, Others, DNA Damage/DNA Repair, Apoptosis, Metabolism, Autophagy, Neuroscience, Cytoskeletal Signaling, Chromatin/Epigenetic, Immunology/Inflammation, Proteases/Proteasome
Bioactivity
Coenzyme Q0 (CoQ0), a potent, orally active ubiquinone compound derived from Antrodia cinnamomea, induces apoptosis and autophagy. It suppresses HER-2/AKT/mTOR signaling, enhancing apoptosis and autophagy mechanisms. Additionally, Coenzyme Q0 regulates NFκB/AP-1 activation and promotes Nrf2 stabilization, contributing to the attenuation of inflammation and redox imbalance. It also exhibits anti-angiogenic activity by downregulating MMP-9/NF-κB and upregulating HO-1 signaling.
Smiles
COC1=C(OC)C(=O)C(C)=CC1=O
Molecular Formula
C9H10O4
Molecular Weight
182.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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