Diethyl phosphate

• Description :

  Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats[1][2][3].

• Product Name Alternative :

  Diethyl phosphoric acid

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H312, H314, H318

• Target :

  Endogenous Metabolite; Interleukin Related

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/Diethyl-phosphate.html

• Purity :

  98.08

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=P(OCC)(O)OCC

• Molecular Formula :

  C4H11O4P

• Molecular Weight :

  154.10

• Precautions :

  H302, H312, H314, H318

• References & Citations :

  [1]Kyogoku Y, et al. The crystal structure of barium diethyl phosphate[J]. Acta Crystallographica, 1966, 21 (1) : 49-57.|[2]Yang F, et al. Effects of Diethyl Phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides, on Serum Lipid, Hormones, Inflammation, and Gut Microbiota. Molecules. 2019 May 24;24 (10) :2003.|[3]Yang FW, et al. Assessment of the endocrine-disrupting effects of diethyl phosphate, a nonspecific metabolite of organophosphorus pesticides, by in vivo and in silico approaches. Environ Int. 2020 Feb;135:105383.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [598-02-7]