Diethyl phosphate

• Description:

  Diethylphosphate (Diethyl phosphoric acid) is an orally active organophosphorus pesticides metabolite. Diethylphosphate can interfere with thyroid hormone-related mechanisms and affect intestinal microbes in rats[1][2][3].

• Product Name Alternative:

  Diethyl phosphoric acid

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H312, H314, H318

• Target:

  Endogenous Metabolite; Interleukin Related

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/Diethyl-phosphate.html

• Purity:

  98.08

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=P (OCC) (O) OCC

• Molecular Formula:

  C4H11O4P

• Molecular Weight:

  154.10

• Precautions:

  H302, H312, H314, H318

• References & Citations:

  [1]Kyogoku Y, et al. The crystal structure of barium diethyl phosphate[J]. Acta Crystallographica, 1966, 21 (1) : 49-57.|[2]Yang F, et al. Effects of Diethyl Phosphate, a Non-Specific Metabolite of Organophosphorus Pesticides, on Serum Lipid, Hormones, Inflammation, and Gut Microbiota. Molecules. 2019 May 24;24 (10) :2003.|[3]Yang FW, et al. Assessment of the endocrine-disrupting effects of diethyl phosphate, a nonspecific metabolite of organophosphorus pesticides, by in vivo and in silico approaches. Environ Int. 2020 Feb;135:105383.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  598-02-7