Mouse Monoclonal IgG1 Anti-3-DG-Imidazolone (Advanced Glycation End Product) [JNH-27]

• Catalog number
  IMI043
• Price
  Please ask
• Size
  50 µg

• Availability
  Please contact us to check the availability
• Immunogen
  3-DG-derived Imidazolone-HSA
• Species reactivity
  not relevant
• Product presentation
  Protein G affinity purified antibody from ascites in stabilized buffer, containing 50% Block Ace (Casein-containing solution, Dainippon Co.) and 0.1% ProClin (Rohm & Haas) as a preservative
• Product category
  Primary Antibody
• Antibody s raised in
  Mouse
• Antibody s isotype
  IgG1
• Antibody s clone
  JNH-27
• Product is supplied as
  liquid concentrate
• Recommended concentration for use
  app. 7 µg/ml (IHC)
• Protein concentration
  0.25 mg/ml
• Tested applications
  IHC(C, P)
• Recommended secondary reagent
  We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005). If higher sensitivity is required VECTASTAIN Elite ABC Mouse IgG (Art. No. PK-6102) or ABC AP Mouse IgG (Art. No. AK-5002) systems are applicable.
• Storage method
  Store at -20°C
• UniProt number
  Go to UniProt/SwissProt
• Litterature
  1. Shibata N, Nagai R, Miyata S, Jono T, Horiuchi S, Hirano A, Kato S, Sasaki S, Asayama K, Kobayashi M. Nonoxidative protein glycation is implicated in familial amyotrophic lateral sclerosis with superoxide dismutase-1 mutation. Acta Neuropathol (Berl). 2000 Sep; 100(3): 275-284. 2. Niwa T, Katsuzaki T, Miyazaki S, Momoi T, Akiba T, Miyazaki T, Nokura K, Hayase F, Tatemichi N, Takei Y. Amyloid beta 2-microglobulin is modified with imidazolone, a novel advanced glycation end product, in dialysis-related amyloidosis.Kidney Int. 1997 Jan;51(1):187-194. 3. Franke S, Niwa T, Deuther-Conrad W, Sommer M, Hein G, Stein G. Immunochemical detection of imidazolone in uremia and rheumatoid arthritis. Clin Chim Acta. 2000 Oct;300(1-2):29-41. 4. Nakamura S, Miyazaki S, Sakai S, Morita T, Hirasawa Y, Niwa T. Localization of imidazolone in the peritoneum of capd patients: a factor for a loss of ultrafiltration. Am J Kidney Dis. 2001 Oct;38(4 Suppl 1):S107-110. 5. Franke S, Dawczynski J, Strobel J, Niwa T, Stahl P, Stein G. Increased levels of advanced glycation end products in human cataractous lenses. J Cataract Refract Surg. 2003 May;29(5):998-1004.
• Tips
  *Gentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
• Other products
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   IgG1   3-DG-Imidazolone   Advanced   Glycation   End   [JNH-27]  
• Gene symbol
  SNORD115-27, IGKV1D-27, RNVU1-27, IGHV7-27, ERVK-27, ERVW-27, SNORD114-27, SNORD116-27, IGLV3-27, IGHD7-27
• Short name
  AGE
• Technique
  Mouse monoclonal, anti-, Mouse, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1
• Species
  Mouse, Mouses
• Alternative name
  3-DG-Imidazolone (Advanced Glycation End Product)
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:33046
• Gene
  SNORD115-27
• Long gene name
  small nucleolar RNA, C/D box 115-27
• Synonyms
  • HBII-52-27
• Locus
  15q11.2
• Discovery year
  2011-08-22
• Entrez gene record
  100036564
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003496
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5751
• Gene
  IGKV1D-27
• Long gene name
  immunoglobulin kappa variable 1D-27 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 1D-27
• GenBank acession
  • Z00004
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28898
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151607

Gene info

• Identity
  HGNC:54431
• Gene
  RNVU1-27
• Long gene name
  RNA, variant U1 small nuclear 27
• Locus
  1q21.2
• Discovery year
  2019-07-26
• Classification
  • Variant U1 small nuclear RNAs

Gene info

• Identity
  HGNC:5663
• Gene
  IGHV7-27
• Long gene name
  immunoglobulin heavy variable 7-27 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable 7-27
  • immunoglobulin heavy variable 7-27 pseudogene
• GenBank acession
  • M99643
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28383
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152070

Gene info

• Identity
  HGNC:44980
• Gene
  ERVK-27
• Long gene name
  endogenous retrovirus group K member 27
• Synonyms gene name
  • endogenous retrovirus group K, member 27
• GenBank acession
  • JZ164909
• Locus
  11q12.3
• Discovery year
  2014-01-03
• Pubmed identfication
  • 23338945

Gene info

• Identity
  HGNC:49315
• Gene
  ERVW-27
• Long gene name
  endogenous retrovirus group W member 27
• Synonyms gene name
  • endogenous retrovirus group W, member 27
• GenBank acession
  • HG421064
• Locus
  14q32.12
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:33015
• Gene
  SNORD114-27
• Long gene name
  small nucleolar RNA, C/D box 114-27
• Synonyms
  • 14q(II-27)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767608
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003220.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33093
• Gene
  SNORD116-27
• Long gene name
  small nucleolar RNA, C/D box 116-27
• Synonyms
  • HBII-85-27
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033439
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003341
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5910
• Gene
  IGLV3-27
• Long gene name
  immunoglobulin lambda variable 3-27
• GenBank acession
  • D86994
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28791
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151171

Gene info

• Identity
  HGNC:5518
• Gene
  IGHD7-27
• Long gene name
  immunoglobulin heavy diversity 7-27
• Synonyms
  • IGHD727
  • DHQ52
• GenBank acession
  • J00256
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28484
• Pubmed identfication
  • 6795593
  • 6101209
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152435

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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