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Mouse Monoclonal IgG1 Anti-AGE (Advanced Glycation End Products) [6D12]

  • Catalog number
    AGE612
  • Product name
    Mouse Monoclonal IgG1 Anti-AGE (Advanced Glycation End Products) [6D12]
  • Size
    10 µg
  • Availability
    Please contact us to check the availability
  • Immunogen
    Advanced Glycation End Products-BSA
  • Specificity
    Positive: Advanced Glycation End Products, AGE-HSA, AGE-BSA, AGE-Hb, AGE-Collagen, AGE-Lys-derivatives (AGE-alpha-Tos-Lys, AGE-alpha-Tos-Lys-o-Me), AGE-monoamino carboxylic acids (AGE-beta-Alanine, AGE-gamma-aminobutyric acid, AGE-epsilon-aminocaproic acid) - negativ: early stages of the Maillard reaction (Schiff's base adducts, Amadori rearrangement products), unmodified protein HSA, BSA, Hb, Collagen, poly-Lys, Lys-derivatives (alpha-Tos-Lys, alpha-Tos-Lys-o-Me), unmodified monoamino carboxylic acids (beta-alanine, gamma-amino butyric acid, epsilon-aminocaproic acid), FFI, Pyrrole aldehyde, Pentosidine.
  • Species reactivity
    not relevant
  • Product presentation
    Protein G affinity purified antibody from ascites in stabilized buffer, containing 50% Block Ace (Casein-containing solution, Dainippon Co.) and 0.1% ProClin (Rohm & Haas) as a preservative
  • Product category
    Primary Antibody
  • Short name
    AGE
  • Antibody s raised in
    Mouse
  • Antibody s isotype
    IgG1
  • Antibody s clone
    6D12
  • Product is supplied as
    liquid concentrate
  • Recommended concentration for use
    ELISA 0.1-0.5 µg/ml; IHC 2 µg/ml
  • Protein concentration
    0.25 mg/ml
  • Positive control
    human lens, arteriosclerotic plaques
  • Tested applications
    IHC, ELISA
  • Recommended secondary reagent
    We recommend the use of Gentaur's Universal Staining System DAB (Art. No. DA005) or AEC (Art. No. AE005), if higher sensitivity is required VECTASTAIN Elite ABC Mouse IgG (Art. No. PK-6102) or ABC AP Mouse IgG (Art. No. AK-5002) systems are applicable.
  • Storage method
    Store at -20°C
  • UniProt number
    Go to UniProt/SwissProt
  • Litterature
    1. Horiuchi S., Araki N., and Morino Y. (1991) Immunological approach to characterize advanced glycation end products of the Maillard reaction: Evidence for the presence of a common stucture. J. Biol. Chem. 266; 7329-7332. 2. Akari N., Ueno N., Chakrabarti B., Morino Y., and Horiuchi S. (1992) Immunochemical evidence of the presence of advanced glycation end products in human lens proteins and its positive correlation with aging. J. Biol. Chem. 267; 10211-10214. 3. Miyata T., Odo O., Inagi R., Iida Y., Araki N., Yamada N., Horiuchi S., Taniguchi N., Maeda, et al. (1993) ß2-Microglobulin modified with advanced glycation end products is a major component of haemodialysis-associated amyloidosis. J. Clin. Invest. 92; 1243-1252. 4. Kume S., Takeya M., Mori T., Araki N., Suzuki H., Horiuchi S., Kodama T., Miyauchi Y., and Takahashi K. (1995) Immunohistochemical and ultrastructural detection of advanced glycation end products in atherosclerotic lesions of human aorta using a novel specific monoclonal antibody. Am J. Pathol. 147; 654-667. 5. Kimura T., Takamatsu J., Ikeda K., Kondo A., Miyakawa T., and Horiuchi S. (1996) Accumulation of advanced glycation end products of the Maillard reaction with age in human hippocampal neurons. Neurosci. Lett. 208; 53-56.
  • Tips
    *Gentaur antibodies are intended for in vitro research use only. They must not be used for clinical diagnostics and not for in vivo experiments in humans or animals.
  • Other products
    Other_products
  • Gene target
    Monoclonal IgG1 AGE Advanced Glycation End Products [6D12]
  • Host
    mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
  • Isotype
    IgG1
  • technique filter
    • Mouse monoclonal
    • anti-
    • Mouse
    • anti
  • Technique
    Mouse monoclonal, anti-, Mouse, anti, antibody to, antibodies, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
  • Alternative technique
    murine, antibodies