Leptin receptor Antibody

• Catalog number
  bs-0961R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Leptin receptor Primary Polyclonal Antibody
• Also known as
  Leptin receptor PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Leptin receptor
• Specificity
  This is a highly specific antibody against Leptin receptor.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  540-590/1165
• Subcellular location
  Extracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human of human Leptin receptor
• Gene ID number
  3953
• Swiss Prot
  P48357
• Tested Applications
  WB, FCM, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Receptor for obesity factor (leptin). On ligand binding, mediates signaling through JAK2/STAT3. Involved in the regulation of fat metabolism and, in a hematopoietic pathway, required for normal lymphopoiesis. May play a role in reproduction. Can also mediate the ERK/FOS signaling pathway (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  OBR; OB-R; CD295; LEP-R; LEPRD; Leptin receptor; HuB219; OB receptor; LEPR; DB
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Gene
  Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  Leptin   receptor  
• Gene symbol
  LEPR, LEPROT, LEPROTL1
• Short name
  Anti-Leptin receptor
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Leptin receptor Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6554
• Gene
  LEPR
• Long gene name
  leptin receptor
• Synonyms
  • OBR
  • CD295
• GenBank acession
  • U43168
• Locus
  1p31.3
• Discovery year
  1996-05-09
• Entrez gene record
  3953
• Pubmed identfication
  • 8548812
  • 8812446
• RefSeq identity
  • NM_002303
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000009115
• Locus Specific Databases
  • LRG_283

Gene info

• Identity
  HGNC:29477
• Gene
  LEPROT
• Long gene name
  leptin receptor overlapping transcript
• Synonyms
  • OBRGRP
  • OB-RGRP
  • VPS55
  • FLJ90360
• Synonyms name
  • leptin receptor gene related protein
  • endospanin-1
  • endospanin
• GenBank acession
  • Y12670
• Locus
  1p31.3
• Discovery year
  2004-11-16
• Entrez gene record
  54741
• Pubmed identfication
  • 9207021
  • 21454707
• RefSeq identity
  • NM_017526
• VEGA ID
  OTTHUMG00000009065

Gene info

• Identity
  HGNC:6555
• Gene
  LEPROTL1
• Long gene name
  leptin receptor overlapping transcript like 1
• Synonyms
  • my047
  • Vps55
• Synonyms name
  • endospanin-2
• GenBank acession
  • AF063605
• Locus
  8p12
• Discovery year
  2000-06-15
• Entrez gene record
  23484
• Pubmed identfication
  • 11342119
• VEGA ID
  OTTHUMG00000163820

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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