Anti - Leptin Receptor (OBR, LEPR, B219, Obese Receptor)
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Catalog numberMBS622422
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Price:
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Size5x0.1 mL
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Products_typeAntibody
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Products_short_name[Leptin Receptor]
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Products_name_syn[Leptin Receptor (OBR, LEPR, B219, Obese Receptor)]
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Other_names[leptin receptor; Leptin receptor; leptin receptor; huB219; OB receptor; OTTHUMP00000010692; OTTHUMP00000010693; OTTHUMP00000010694; OTTHUMP00000010695; leptin receptor; HuB219; OB receptor]
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Other_gene_names[LEPR; LEPR; OBR; OB-R; CD295; LEP-R; DKFZp686B1731; DB; OBR]
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ClonalityPolyclonal
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ReactivityMouse, Rat
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SpecificityMouse sequence is unique to the OBRb long form. It is not found in OBR isoforms a and c-f. It is 100% conserved rat, 84% in porcine, turkey and chicken, 76% in sheep human and monkey OBRb. Has no significant homology to gp130.
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PuritySerum
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FormSerum Supplied as a liquid, neat serum, 40% glycerol.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationELISA
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GeneHuman or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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Gene target
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Gene symbolLEPR
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Short nameAnti - Leptin Receptor (OBR, LEPR, B219, Obese Receptor)
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Techniqueanti, antibody to
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HostHost: Rabbit Source: Mouse
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IsotypeIgG
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Alternative nameantibody to - Leptin Receptor (OBR, leptin receptor, B219, Obese Receptor)
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Alternative techniqueantibodies
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Alternative to gene targetleptin receptor, CD295 and LEP-R and LEPRD and OB-R and OBR, LEPR and IDBG-99469 and ENSG00000116678 and 3953, identical protein binding, Extracellular, Lepr and IDBG-167734 and ENSMUSG00000057722 and 16847, LEPR and IDBG-638266 and ENSBTAG00000005910 and 497205,785813
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Gene info
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Identity
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Gene
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Long gene nameleptin receptor
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-05-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data