Leptin Receptor antibody
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Catalog number70R-34438
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PricePlease ask
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Size100 µg
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CategoryPrimary Antibody
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Antibody SubtypePolyclonal Antibodies, Purified
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Area of researchNutrition & Metabolism
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Type of ImmunogenLeptin Receptor antibodies were raised in Rabbit using synthesized non-phosphopeptide derived from human Leptin Receptor around the phosphorylation site of tyrosine 1141 (A-S-YP-M-P) .
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Raised inRabbit
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SpecificityLeptin Receptor antibody detects endogenous levels of total Leptin Receptor protein
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Cross ReactivityMouse
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IsotypesIgG
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Concentration1 mg/ml
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Form BufferProvided in PBS buffer (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl with 0.02% NaN3 and 50% glycerol
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StorageAliquot and store at -20 deg C. Avoid repeated freeze thaw cycles
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Shipping conditionsBlue Ice
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Tested forWB; ELISA
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Usage RecommendationsWB: 1:500-1:3000, ELISA: 1:20000
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PropertiesIf you buy Antibodies supplied by fitzgerald they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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GeneHuman or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.
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DescriptionThe receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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French translationanticorps
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Gene target
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Gene symbolLEPR, LEPROT, LEPROTL1
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Short nameLeptin Receptor antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameRabbit polyclonal Leptin Receptor antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameleptin receptor
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-05-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Immunoglobulin like domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameleptin receptor overlapping transcript
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameleptin receptor overlapping transcript like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-06-15
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Entrez gene record
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Pubmed identfication
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
