anti-HDAC4 / HDAC5 / HDAC9 (Ab 246 / 259 / 220) Antibody

• Catalog number
  79-424
• Price
  Please ask
• Size
  0.1 mg

• Gene info
  Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
• Gene names
  HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A, RNF1, HD4/HD5/HD9
• Antibodie s label
  unlabelled serum
• Purity
  Antibodies were purified by affinity-chromatography using epitope-specific peptide.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Spicific to
  This antibody detects endogenous level of total HDAC4/HDAC5/HDAC9 protein.
• Antigen
  HDAC4/HDAC5/HDAC9 (Ab-246/259/220) antibody was made against a peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9.
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
• Suspention pH azide
  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Keep at
  Store antibody at -20 grades C for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  153085395 / 62750349 / 7662280
• Ncbi nr
  NP_006028.2 / NP_001015053.1 / NP_055522.1
• KDa
  140, 124 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  9759 / 10014 / 9734
• GENE symbol
  HDAC4 HDAC5 HDAC9
• Antigene name
  histone deacetylase 4 / histone deacetylase 5 / histone deacetylase 9
• Source
  Homo sapiens
• Protein nr
  P56524 Q9UQL6 Q9UKV0
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HDAC4   HDAC5   HDAC9   246   259   220  
• Gene symbol
  HDAC9-AS1, HDAC4-AS1, HDAC9, HDAC5, HDAC4
• Short name
  anti-HDAC4 / HDAC5 / HDAC9 (Ab 246 / 259 / 220) Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toHDAC4 / histone deacetylase 5 / histone deacetylase 9 (Antibody 246 / 259 / 220) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  histone deacetylase 9, HD7 and HD7b and HD9 and HDAC and HDAC7 and HDAC7B and HDAC9B and HDAC9FL and HDRP and MITR, HDAC9 and IDBG-9049 and ENSG00000048052 and 9734, NAD-dependent histone deacetylase activity (H3-K18 specific), nuclei, Hdac9 and IDBG-134566 and ENSMUSG00000004698 and 79221, HDAC9 and IDBG-629964 and ENSBTAG00000003808 and 535415

Gene info

• Identity
  HGNC:40664
• Gene
  HDAC9-AS1
• Long gene name
  HDAC9 antisense RNA 1
• Locus
  7p21.1
• Discovery year
  2019-08-07
• Entrez gene record
  105375176
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:54064
• Gene
  HDAC4-AS1
• Long gene name
  HDAC4 antisense RNA 1
• Locus
  2q37.3
• Discovery year
  2018-09-27
• Entrez gene record
  101928111
• RefSeq identity
  • NR_135575
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:14065
• Gene
  HDAC9
• Long gene name
  histone deacetylase 9
• Synonyms
  • KIAA0744
  • HDAC
  • MITR
  • HD7
  • HDAC7B
• GenBank acession
  • AF124924
• Locus
  7p21.1
• Discovery year
  2002-09-06
• Entrez gene record
  9734
• Pubmed identfication
  • 10523670
  • 10487760
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000152487

Gene info

• Identity
  HGNC:14068
• Gene
  HDAC5
• Long gene name
  histone deacetylase 5
• Synonyms
  • KIAA0600
  • NY-CO-9
  • FLJ90614
• GenBank acession
  • AF249731
• Locus
  17q21.31
• Discovery year
  2000-11-28
• Entrez gene record
  10014
• Pubmed identfication
  • 10220385
  • 9610721
• RefSeq identity
  • NM_001015053
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000181806

Gene info

• Identity
  HGNC:14063
• Gene
  HDAC4
• Long gene name
  histone deacetylase 4
• Synonyms gene
  • BDMR
• Synonyms gene name
  • brachydactyly-mental retardation syndrome
• Synonyms
  • KIAA0288
  • HDAC-A
  • HDACA
  • HD4
  • HA6116
  • HDAC-4
• GenBank acession
  • AB006626
• Locus
  2q37.3
• Discovery year
  2000-11-28
• Entrez gene record
  9759
• Pubmed identfication
  • 10206986
  • 10220385
  • 20691407
• RefSeq identity
  • NM_006037
• Classification
  • Histone deacetylases, class IIA
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133344

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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