Recombinant Rat Interleukin-2/IL-2 (C-6His)

Description

Recombinant Rat Interleukin-2 is produced by our Mammalian expression system and the target gene encoding Ala21-Gln155 is expressed with a 6His tag at the C-terminus.
Species reactivity

Rat
Origin

Human cells
Peptide sequence

APTSSPAKETQQHLEQLLLDLQVLLRGIDNYKNLKLPMMLTFKFYLPKQATELKHLQCLENELGALQRVLDLTQSKSFHLEDAGNFISNIRVTVVKLKGSENKFECQFDDEPATVVEFLRRWIAICQSIISTMTQHHHHHH
Estimated molecular weight

16.3
Protein purity

Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level

Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
Shipping condition

Dry Ice/ice packs
Package form

Supplied as a 0.2 µm filtered solution of 5mM NaH2PO4, 5mM Citric acid, 150mM NaCl, pH4.0.
Storage conditions

Store at below -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles.
Reconstitution conditions

See included datasheet or contact us for more information.
UniProt number

P17108
Other related products
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus
Source

Recombinants or rec. proteins
Group

recombinants

Gene target

Interleukin-2/IL-2 C-6His
Gene symbol

IL2, IL36G, IL25, IL22, IL18, IL37, IL1RAPL2, IL6R, IL17C, IL17D
Short name

Recombinant Interleukin-2/IL-2 (C-6His)
Technique

Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
Host

Rat
Species

Rat, Rats
Alternative name

Recombinant Rat IL-2 (C-6His)
Alternative technique

rec

Identity

HGNC:5997
Gene

IL1RAPL2
Long gene name

interleukin 1 receptor accessory protein like 2
Synonyms
- IL-1R9
- TIGIRR-1
- IL1RAPL-2
- IL1R9
GenBank acession
- AF181285
Locus

Xq22.3
Discovery year

1999-11-19
Entrez gene record

26280
Pubmed identfication
- 10757639
RefSeq identity
- NM_017416
Classification
- TIR domain containing
- Immunoglobulin like domain containing
- Interleukin receptors
VEGA ID

OTTHUMG00000022141
Locus Specific Databases
- Global Variome shared LOVD

Identity

HGNC:6019
Gene

IL6R
Long gene name

interleukin 6 receptor
Synonyms
- CD126
- IL-6R
- IL-1Ra
- IL6RA
- gp80
Synonyms name
- membrane glycoprotein 80
- interleukin 6 receptor subunit alpha
GenBank acession
- X12830
Locus

1q21.3
Discovery year

2001-06-22
Entrez gene record

3570
Pubmed identfication
- 8428753
- 12633863
RefSeq identity
- NM_000565
Classification
- CD molecules
- Interleukin receptors
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000036073

Name

Primary Cell Culture
Concept

Scope note: The initial culturing of cells derived directly from fresh TISSUES.
Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data