RAGE, human, Receptor for Advanced Glycation End Products

• Catalog number
  RAGE001-200
• Price
  Please ask
• Size
  100 µl

• Clone
  NA
• Species Reactivity
  Human, cross-reactivity with mouse, rat and bovine receptor expected
• Product Types
  Primary Antibodies
• Positive Control
  human renal tissue
• Immunogen
  Synthetic peptide corresponding to human RAGE (42-59)
• Working Concentration
  (liquid conc.) IHC (P) (1:400), ELISA (1:10000-1:260000), WB 1:2000
• Concentration
  NA
• Incubation Time
  60 min at RT or 18 hr at 2-8°C
• Application
  IHC(P), ELISA , WB
• Storage
  -20°C
• UniProt
  Q15109 (RAGE_HUMAN)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  RAGE   Receptor   for   Advanced   Glycation   End   Products  
• Gene symbol
  AGER, MOK
• Short name
  RAGE, , Receptor for Advanced Glycation End Products
• Host
  Goat
• Isotype
  NA
• Species
  Human, Humans
• Alternative name
  RAGE, H. sapiens, Receptor to measure Advanced Glycation End Products

Gene info

• Identity
  HGNC:320
• Gene
  AGER
• Long gene name
  advanced glycosylation end-product specific receptor
• Synonyms
  • RAGE
  • SCARJ1
  • sRAGE
• Synonyms name
  • receptor for advanced glycation end-products
• GenBank acession
  • M91211
• Locus
  6p21.32
• Discovery year
  1994-10-17
• Entrez gene record
  177
• Pubmed identfication
  • 7713518
• RefSeq identity
  • NM_001136
• Classification
  • Scavenger receptors
  • C2-set domain containing
• VEGA ID
  OTTHUMG00000031120

Gene info

• Identity
  HGNC:9833
• Gene
  MOK
• Long gene name
  MOK protein kinase
• Synonyms gene
  • RAGE
• Synonyms gene name
  • renal tumor antigen
• Synonyms
  • RAGE1
  • STK30
• GenBank acession
  • AB022694
• Locus
  14q32.31
• Discovery year
  1995-05-10
• Entrez gene record
  5891
• Pubmed identfication
  • 8781117
  • 10421840
• VEGA ID
  OTTHUMG00000164896

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